Perineural injection of platelet-rich plasma (PRP) may improve pain and numbness associated with diabetic peripheral neuropathy (DPN), and enhance peripheral nerve function, according to study results published in Pain Medicine.
This review evaluates current clinical literature on the use of platelet-rich plasma (PRP), in order to develop evidence-based recommendations for various musculoskeletal indications. Abundant high-quality evidence supports the use of PRP injection for lateral epicondylitis and for osteoarthritis of the knee.
Amid extensive debate, evidence surrounding the use of platelet-rich plasma (PRP) for musculoskeletal injuries has rapidly proliferated, and an overall assessment of efficacy of PRP across orthopedic indications is required.
Platelets are an excellent source of GFs in their naturally-occurring and biologically determined ratio, and are successful in acute wound healing. The application of platelet-rich plasma (PRP) has been proven to enhance early wound healing and healing in diabetic ulcers.
Platelet-rich plasma (PRP) is defined as a volume of plasma with a platelet concentration higher than the average in peripheral blood. Many basic, preclinical and even clinical case studies and trials report PRP’s ability to improve musculoskeletal conditions including osteoarthritis, but paradoxically, just as many conclude it has no effect. The purpose of this narrative review…
Androgenic alopecia (AGA) is a chronic, progressive condition affecting millions of individuals worldwide. Treatment modalities for AGA are limited and our understanding of the pathophysiology underlying the disease is still developing. Platelet-rich plasma (PRP) has demonstrated efficacy in limiting AGA.
The purpose of this narrative review is to discuss the available relevant evidence that supports the clinical use of PRP in osteoarthritis, highlighting those variables we perceive as critical. Here, recent systematic reviews and meta-analyses were used to identify the latest randomized controlled trials (RCTs) testing a PRP product as an intra-articular treatment for knee osteoarthritis, compared with an intra-articular control (mostly hyaluronic acid).
Platelet-rich plasma (PRP) has been shown to be effective in treating partial tears of the ulnar collateral ligament (UCL) of the elbow in overhead throwing athletes, but it is still unknown whether it has a role in complete tears. The aim of this study was to assess the effectiveness of PRP in treating complete as well as partial UCL tears.