Effects of platelet-rich plasma on pain and muscle strength in patients with knee osteoarthritis.



The PRP group showed a significant reduction in the WOMAC-pain and -total scores compared to normal saline group (p < 0.05). Although a significantly greater percentage of knee strength (extensor > flexor) was found in the PRP group during a longer follow-up period, PRP treatment resulted in insignificant differences in muscle strength compared to normal saline.


PRP treatment significantly improves pain, stiffness, and disability in patients with knee OA compared to normal saline treatment. Additional strength training is recommended to enhance muscle strength recovery.

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